Axonal Transport and Neurodgenerative Disorders (ICTS Program, 2013)

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source: International Centre for Theoretical Sciences    2013年6月7日
PROGRAM LINK: http://www.icts.res.in/program/ATND2013
DESCRIPTION:
Neurodegeneration, a broad symptom which arises out of several different dysfunctions, is prevalent in aging populations, and it mostly affects people after 50 years of age. There are both hereditary and sporadic cases. Alzheimer's, Parkinson's, Huntington's, Charcot Marie Tooth Type 2A (CMT2A), and a variety of different dementia are some examples. Recent research suggests that aberrant intracellular transport and mutations in the motor protein genes can induce such disorders in model organisms and humans. Recent reports also indicate that loss of mitochondrial transport, as well as the slow axonal transport, can induce dementia and neurofibrillary plaques in the brain. In view of these and other related developments, a large body of research has been launched world-wide to elucidate the connection between defective axonal transport and neurodegeneration. This ICTS program, jointly organized by faculties from TIFR, IIT Bombay and UC San Diego, will highlight this new area of research. The program will be organized in two parts:
(i) Advanced School January 13-19, 2013; Venue: IIT Bombay
(ii) Workshop January 20-26, 2013; Venue: The Club Mahabaleshwar
It will be focused on exploring the emergent link between Axonal Transport and Neurodegeneration by well-known and highly acclaimed experts in the field from India and abroad to train and motivate the PhD and postdoctoral students, as well as young faculty. The workshop is organized as a part of the "Mahabaleshwar Seminars on Modern Biology" series and will be concluded with the annual meeting of the Molecular Motors, Transport and Trafficking (M2T2) group

Ambarish Kunwar(1) - Computational Techniques to Understand Single Motors 1:34:19
Ambarish Kunwar(2) - Computational Techniques to Understand Single Motors 24:01
Anna Akhmanova (1) - Regulation of microtubule dynamics 1:01:10
Anna Akhmanova (2)- A zoo at the tip 1:26:15
Bill Saxton (1) - Motor Proteins-biophysical characteristics and force generation mechanisms 1:23:52
Bill Saxton (2) - Cytoplasmic streaming: how motors can move fluid 1:00:57
Gautam Menon - Diffusion, Noise, and Brownian Motion 1:11:50
John Mercer (1) - Intracellular transport by (and other functions of) Myosins. 1:08:26
John Mercer (2)- Myosin V at the synapse and in RNA transport between cells 52:16
Krishanu Ray - Selective Axonal Transports by Kinesin-2 1:02:03
Michel Steinmetz - Molecular mechanisms of microtubule tip tracking 59:23
Peter Baas (1) - Microtubule organization in neurons, neuron development and disease 1:00:01
Peter Baas (2) - Microtubule organization in neurons, neuron development and disease 51:16
Peter Baas (3) - Microtubule Polarity Orientation in Neurons 39:05
Peter Baas (4) - Microtubule Polarity Orientation in Neurons 19:05
Peter Baas (5)- Mitotic Motors co-Regulate Microtubule Organization in Axons and Dendrites 1:40:03
Peter Baas (6)- Mitotic Motors co-Regulate Microtubule Organization in Axons and Dendrites 1:44:58
Peter Baas (7)- Mitotic Motors co-Regulate Microtubule Organization in Axons and Dendrites 40:30
peter hollenbeck (1) - Historical perspectives and current questions on axonal transport 1:00:01
peter hollenbeck (2) - Mitochondrial Transport, Metabolism and ROS Production in Disease Models 57:45
peter hollenbeck (3-1) - Location and Organization of Features of the Mitochondrial 59:04
peter hollenbeck (3-2) - Location and Organization of Features of the Mitochondrial 55:59
Promod Pullarkat (1-1) - Cellular force measurements. 57:45
Promod Pullarkat (1-2) - Cellular force measurements. 1:00:01
Promod Pullarkat (2) - Shape instabilities in axons 53:42
Ranjith P - Basics of Monte Carlo Simulations 1:00:01
Roop Mallik (1) - Biopysical Measurements of Motor function 1:00:01
Roop Mallik (2) - Force measurements on a single motor protein 54:56
Roop Mallik (3) - Tug of War: Motors Fight it out inside a cell 1:00:01
Sandhya Koushika - Regulation of synaptic vesicle transport 55:24
Scott Brady (1) - Neuron structure-function and historical research on axonal transport 1:00:01
Scott Brady (2) - Adult-Onset Neurodegeneration as Dysferopathies 1:20:20
Subhojit Roy (1) - Human neurodegenerative neuropathology 1:20:11
Subhojit Roy (2)- The Curious Case of the Soluble Protein 1:13:39
Subhojit Roy (3)- The Curious Case of the Soluble Protein 1:16:28
Yishi Jin (1) - Genetic approaches to synapse formation 1:17:01
Yishi Jin (2) - Genetic approaches to synapse formation 1:04:36
Yishi Jin (3) - Genetic approaches to synapse formation 1:19:16