Rethinking Cholesterol: Drug Developments and Lifestyle Choices

source: Harvard University        2015年9月25日
For decades, statins have served as the “go-to” drug for patients with high cholesterol. Now, a new class of cholesterol-reducing drugs, PCSK9 inhibitors, just approved by the FDA, offers a possible alternative to statins. Adding to the changing landscape of cholesterol treatment are recommendations from the American Heart Association and American College of Cardiology, issued in 2013, that dramatically expanded the number of people who could potentially receive statins to prevent heart attack or stroke. Together, these developments have renewed focus on cholesterol as a major health issue. What role might this new class of cholesterol-lowering drugs play? How might their cost impact access and insurance coverage? What lifestyle factors, especially dietary fats, influence the prevention and treatment of cholesterol-related risk factors?

Part of The Dr. Lawrence H. and Roberta Cohn Forums, this webcast was presented September 24, 2015 in Collaboration with Reuters and in Association with Harvard Health Publications.
Watch the entire series from The Forum at Harvard T.H. Chan School of Public Health at www.ForumHSPH.org.
Image Credit: iStockphoto.com l janulla

Organic Chemistry (Spring 2015)--Susan King / UC Irvine

# click the upper-left icon to select videos from the playlist

source: UCIrvineOCW      上次更新日期：2015年6月22日
UCI Chem 51C: Organic Chemistry (Spring 2015)
Lec 01. Organic Chemistry --Carboxylic Acids & the Acidity of the O-H Bond
View the complete course: http://ocw.uci.edu/courses/chem_51c_o...
Terms of Use: http://ocw.uci.edu/info
More courses at http://ocw.uci.edu
Description: This is the third (and final) quarter of the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.
Organic Chemistry (Chem 51C) is part of OpenChem: http://ocw.uci.edu/collections/open_c...

Lec. 01: Carboxylic Acids 38:26
Lec. 02: Preparation of Carboxylic Acids 50:19
Lec. 03: Hydride Reagents and Addition to Carbonyls 49:52
Lec. 04: Hydride Reagents and Addition to Carbonyls Part 2 49:58
Lec. 05: Addition of Organometallic Reagents to Carbonyls 49:31
Lec. 06: Alpha-Beta Unsaturated Carbonyl Compounds 50:24
Lec. 07: Aldehydes & Ketones: Nucleophilic Substitution 50:26
Lec. 08: Addition of Water, Alcohol & Cyanide 49:21
Lec. 09: Wittig Reaction 49:13
Lec. 10: Electrophilic Addition Reactions of Type 2 Carbonyl Compounds 50:31
Lec. 11: Reaction of Esters 46:13
Lec. 12: Reactions of Carboxylic Acids 50:46
Lec. 13: Substitution Reactions of Carbonyl Compounds at the α-Carbon 47:57
Lec. 14: Reactions at the Alpha-Carbon 50:44
Lec. 15: Alternatives to Direct Alkylation of Enolate Ions 49:01
Lec. 16: Alylation of Acetic Acids 48:36
Lec. 17: Carbonyl Condensation Reactions 49:26
Lec. 18: The Claisen Condensation 50:42
Lec. 19: Synthesis with Claisen Condensation 49:54
Lec. 20: The Robert Annulation & Amines 44:21
Lec. 21: Acidity & Basicity of Amines 50:29
Lec. 22: Preparation of Amines 48:43
Lec. 23: Nucleophile Aromatic Substitution to Aniline Rings 47:11
Lec. 24: Fischer Projections 49:14
Lec. 25: Properties of Anomers - Mutarotation 50:30
Lec. 26: Oxidation Reactions of Sugars 47:58
Lec. 27: Polysaccharides 33:30

Organic Chemistry (Fall 2014)--Susan King / UC Irvine

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source: UCIrvineOCW          2015年1月26日
UCI Chem 51A Organic Chemistry (Fall 2014)
View the complete course: http://ocw.uci.edu/courses/chem_51a_o...
Terms of Use: http://ocw.uci.edu/info.
More courses at http://ocw.uci.edu
Description: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.

UC Irvine OpenCourseWare 0:22
Lecture 2 49:21
Lecture 3 50:36
Lecture 4 40:19
Lecture 5 50:23
Lecture 6 50:31
Lecture 7 50:36
Lecture 8 51:27
Lecture 9 44:36
Lecture 10 43:17
Lecture 11 51:55
Lecture 12 51:01
Lecture 13 50:13
Lecture 14 50:05
Lecture 15 45:41
Lecture 16 45:33
Lecture 17 51:10
Lecture 18 47:53
Lecture 19 48:53
Lecture 20 49:05
Lecture 21 48:10
Lecture 22 50:04
Lecture 23 50:29
Lecture 24 46:50
Lecture 25 46:23
Lecture 26 50:19
Lecture 27 50:14
Lecture 28 42:49

Judith Butler, Avital Ronell and Laurence Rickels. Kafka's Before The La... (2012)

source: European Graduate School      2012年3月1日
http://www.egs.edu/ Judith Butler, Avital Ronell and Laurence Rickels talking about paternal authority and psychoanalysis in Kafka's writings. In this lecture, Laurence Rickels, psychoanalyst and author, discusses the role of libido in judgment, the impossibility of writing, the Oedipus complex and the imperative to enjoy in relationship to Franz Kafka, Jacques Lacan, Sigmund Freud, Walter Benjamin, Jacques Derrida, Martin Luther, Gilles Deleuze and Felix Guattari focusing on parables, paradoxes, commandments, desire, death drive, sexual difference, the superego, performativity and minor literature. Public open lecture for the students and faculty of the European Graduate School EGS Media and Communication Studies department program Saas-Fee Switzerland Europe. 2011. Judith Butler, Avital Ronell and Laurence Rickels.

Avital Ronell and Judith Butler. Psychoanalysis, authority and discernme... (2014)

source: European Graduate School      2014年1月16日
http://www.egs.edu/ Avital Ronell and Judith Butler, talking about psychoanalysis, authority and discernment. In the lecture Avital Ronell and Judith Butler discuss the concepts of Freud, Goethe, death drive, guilt in relationship to Heidegger, Hannah Arendt, Korjeve, Plato, super ego, suicide, focusing on authority. Public open lecture for the students and faculty of the European Graduate School EGS Media and Communication Studies department program Saas-Fee Switzerland Europe 2013 Avital Ronell and Judith Butler.

Judith Butler, Avital Ronell and Laurence Rickels. Bringing Down Metaphy... (2012)

source: European Graduate School      2012年3月12日
http://www.egs.edu/ Judith Butler, Avital Ronell and Laurence Rickels talking about Kafka and the collapse of metaphysics. In this lecture, Avital Ronell, philosopher and author, discusses the play of presence and absence, the politics of friendship, the problem of departure and arrival, the relationship between psychoanalysis and literature, and the reciprocity of calling and being called in relationship to Franz Kafka, Jacques Lacan, Sigmund Freud, Walter Benjamin, Jacques Derrida, Martin Luther, Michel Foucault and Martin Heidegger focusing on the letter, destiny, Gesicht, history, authority, law, the panopticon, the Event, Abraham, hope, impossibility and laughter. Public open lecture for the students and faculty of the European Graduate School EGS Media and Communication Studies department program Saas-Fee Switzerland Europe. 2011. Judith Butler, Avital Ronell and Laurence Rickels.

How folding paper can get you to the moon - Adrian Paenza

source: TED-Ed    2012年4月19日
View full lesson: http://ed.ted.com/lessons/how-folding...
Can folding a piece of paper 45 times get you to the moon? By seeing what happens when folding just one piece of paper, we see the unbelievable potential of exponential growth. This lesson will leave you wanting to grab a piece of paper to see how many times you can fold it!
Lesson by Adrian Paenza, animation by TED-Ed.

Noam Chomsky: Who Owns the World? Resistance and Ways Forward

source: ExplodedView MEF    2012年11月2日
Noam Chomsky delivered a lecture at University of Massachusetts on September 27th, 2012.