lectures/ideas: 05/31/17

2017-05-31

National Human Genome Research Institute (videos of April 2017)

source: National Human Genome Research Institute

59:12 Pharmacogenetics - Victoria Pratt April 13, 2017 - Webinars for Health Insurers and Payers: Understanding Genetic Testing
More: https://www.genome.gov/27563343/

1:01:50 NHGRI's Oral History Collection: Interview with Charles Rotimi For more than two decades, Charles Rotimi, Ph.D., chief of the Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch at the National Human Genome Research Institute
(NHGRI), has studi...

53:22 NHGRI's Oral History Collection: Interview with Current and Former NHGRI Directors - Part II In 2014 and 2015, the National Human Genome Research Institute (NHGRI) filmed a panel discussion with former directors James Watson, Ph.D. and Francis Collins, M.D., Ph.D., and current director Eri...

1:32:57 NHGRI's Oral History Collection: Interview with Current and Former NHGRI Directors - Part I In 2014 and 2015, the National Human Genome Research Institute (NHGRI) filmed a panel discussion with former directors James Watson, Ph.D. and Francis Collins, M.D., Ph.D., and current director Eri...

1:20:49 NHGRI's Oral History Collection: Interview with David Bentley David Bentley, Ph.D., is chief scientist at Illumina Inc., where he develops new DNA sequencing technology for fast, accurate sequencing of complex genomes. This oral history follows Dr. Bentley’s ...

1:55:35 NHGRI's Oral History Collection: Interview with Maynard Olson Maynard Olson, Ph.D., professor of Genome Sciences and Medicine at the University of Washington in Seattle, is a major figure in genomics research, and his research involving large-scale genome ana...

1:33:21 NHGRI's Oral History Collection: Interview with Ewan Birney Ewan Birney, Ph.D., co-director of the European Molecular Biology Laboratory’s European Bioinformatics Institute, played a vital role in annotating the genome of human, mouse, chicken and several o...

46:55 NHGRI's Oral History Collection: Interview with Howard McLeod Howard McLeod, Pharm.D., is the founding medical director of the Moffitt Cancer Center’s DeBartolo Family Personalized Medicine Institute and a senior member in its Department of Cancer Epidemiolog...

Wiring up the brain: How axons navigate (Christine Holt)

source: The Royal Society 2017年4月3日
Ferrier Prize Lecture 2017 given by Professor Christine Holt FMedSci FRS
The brain is made up of billions of nerve cells (neurons) that are wired together by axons and dendrites. The precision of this wiring allows us to accurately sense, interpret and interact with the outside world, which is crucial for survival. Many neurons are positioned far away from the targets so they face the formidable task of sending out an axon that must navigate correctly over a long distance to find its targets. This key step in wiring the brain, called axon guidance, occurs early in embryonic development mostly before birth in humans.
In this lecture, Professor Holt will describe work on how the eye makes its long-distance connections with the brain. She will discuss general mechanisms of guidance and the discovery that RNA-based mechanisms inside axons help to establish and maintain neural circuitry.
The lecture was recorded on March 2 2017 at the Royal Society. For more events like this, see our schedule - http://ow.ly/KhTi306gTN1

Risk and Uncertainty in Exploration for Oil and Gas January 2017

source: GeologicalSociety 2017年3月29日
The fundamental requirements for the entrapment of oil and gas are the presence of a mature source rock, migration of those hydrocarbons from there into a trap, which contains an effective reservoir rock and an appropriate seal. There may be a difference of many millions of years in age of the source, reservoir and seal horizons and the timing of hydrocarbon migration and juxtaposition of these rocks to form a trap is critical.
Once formed, many traps may be destroyed or leak, due to later tectonics. When prospects are worked up and assessed, the overall “Chance of Success” is calculated on the basis of the probability of the presence and effectiveness of the source, reservoir and trap. This describes the overall ‘risk’ of finding hydrocarbons within the range estimated and this may vary from 10% in frontier basins to 30—50% in proven basins.
There is also ‘uncertainty’, which describes the range of outcomes, even when, say the reservoir rock is found to be present. How thick is it? How porous and permeable? Is the original depositional facies as predicted? How connected is it across the prospect?
There is also uncertainty even when hydrocarbons are found, as only a certain amount of appraisal wells can be afforded to establish the range of reserves, before making a multi-billion-dollar decision to develop the field.
Above surface uncertainty also exists. The oil and gas business is a capital intensive, long term business. An oil or gas field may have a life of 5 to 50 years, depending on size and economics. There will be uncertainty of future oil price, government tax rates and in some cases, the future political stability of the host country.
Environmental sensitivity, community relationships and ‘licence to operate’ are all key aspects which must also be assessed. And of course, the impact of fossil fuels on global warming and climate change, is now also a firm part of the context for any decisions, as the world needs to move to a lower carbon environment.

Speaker: Malcolm Brown, President of the Geological Society
After graduating from Kingston Polytechnic (1976), with a BSc in Geology, Malcolm worked in Libya and Saudi Arabia before completing an MSc in Petroleum Geology at Imperial College (1982). He worked at British Gas / BG Group for over 30 years as it evolved from state owned utility to successful international business and was Executive Vice President, Exploration.
Malcolm became a Fellow in 1982, served on Council between 2009 and 2012 and became a Chartered Geologist in 2013. He took over as President of the Society in 2016.

Vernon Bogdanor--The Monarchy (Gresham College)

# playlist: click the video's upper-left icon

source: GreshamCollege 2016年12月30日
The transcript and downloadable versions of the lecture are available from the Gresham College website: http://www.gresham.ac.uk/lectures-and...
Website: http://www.gresham.ac.uk
Twitter: http://twitter.com/GreshamCollege
Facebook: https://www.facebook.com/greshamcollege
Instagram: http://www.instagram.com/greshamcollege

Queen Victoria - Professor Vernon Bogdanor 49:12
Queen Victoria was the first constitutional monarch.
During her reign the power of the monarchy declined but its influence grew. When Victoria came to the throne, the monarchy was probably less popular than at any time since the seventeenth century. By the end of her reign, it had been raised to a level of prestige and affection which it has never lost. The Crown had become the symbol not only of British nationhood but also of Empire. How did this come about?
King Edward VII 55:32
King George V  1:01:02
King Edward VIII  58:08
King George VI  49:19
Queen Elizabeth II 52:39

Bold Ideas in Medicine by Christopher Whitty (Gresham College)

# click the upper-left icon to select videos from the playlist

source: GreshamCollege 2016年12月8日
The treatment for people with many cancers has been transformed in the last two decades, and further major improvements are expected to occur over the next twenty years. http://www.gresham.ac.uk/lectures-and...
Improved surgery and radiotherapy have been joined by less toxic chemotherapy targeting specific genetic abnormalities in cancer cells. Better genetic understanding of cancer and harnessing the immune system to fight disease are among the approaches revolutionising a group of diseases once seen as incurable.
The transcript and downloadable versions of the lecture are available from the Gresham College website: http://www.gresham.ac.uk/lectures-and...
Gresham College has been giving free public lectures since 1597. This tradition continues today with all of our five or so public lectures a week being made available for free download from our website. There are currently over 2,000 lectures free to access or download from the website.
Website: http://www.gresham.ac.uk
Twitter: http://twitter.com/GreshamCollege
Facebook: https://www.facebook.com/greshamcollege
Instagram: http://www.instagram.com/greshamcollege

The Treatment of Cancer - Professor Christopher Whitty 55:52
The Prevention of Cancer 52:36
The Eradication of Infectious Diseases 49:47

Structure vs. Randomness (Simons Institute)

# click the upper-left icon to select videos from the playlist

source: Simons Institute 2017年4月10日
This workshop will focus on a phenomenon observed in harmonic analysis, ergodic theory, analytic number theory, graph theory, complexity theory, additive combinatorics and cryptography, according to which arbitrary objects can be well approximated by a combination of a small number of pseudorandom objects. In the study of higher-order Fourier analysis, this corresponds to approximating every function by a combination of structured functions plus a function of small Gowers norm; in graph theory it corresponds to Szemeredi’s regularity lemma; in cryptography it corresponds to approximating distributions dominated by a pseudorandom distribution by distributions of high min-entropy; and so on.
The workshop will bring together researchers working on such decomposition results in different areas and with different motivations, who often use technically similar methods.
For more information, please visit https://simons.berkeley.edu/workshops/pseudorandomness2017-3
These presentations were supported in part by an award from the Simons Foundation.

Algorithmic Dense Model Theorems and Weak Regularity 34:13 Russell Impagliazzo, UC San Diego https://simons.berkeley.edu/talks/rus...
Sum of Squares Lower Bounds for Refuting Any CSP 30:31
Large Deviations for Arithmetic Progressions 58:51
Trading Information Complexity for Error 29:05
Sparse Dense Dichotomy and Liquid Graphs 25:39
The Entropy Decrement Method and the Erdos Discrepancy Problem 57:37
Vinogradov's Three Primes Theorem with Primes from Special Sets 1:01:44
Additive Structure of Sets of Fourier Coefficients 1:02:35
On Structural Properties of Low Threshold Rank Graphs 35:01
Hidden Irregularity Versus Hidden Structure: The Emergence of the Johnson Graphs 1:06:48
Hidden Irregularity Versus Hidden Structure: The Emergence of the Johnson Graphs 44:26
Random High-Dimensional Combinatorial Objects 1:04:52
Positional Games and Randomness 1:02:09
Labeling the Complete Bipartite Graph with No Zero Cycles 58:07
Unavoidable Patterns in Words 57:05
True Complexity of Multilinear Systems 1:00:50

Simons Institute Open Lectures, Spring 2017

# click the upper-left icon to select videos from the playlist

source: Simons Institute 2017年2月15日
The Simons Institute Open Lectures are aimed at a broad scientific audience and specialist seminars associated with particular programs.
For more information, please visit https://simons.berkeley.edu/events/openlectures.
These presentations were supported in part by an award from the Simons Foundation.

Does Randomness Solve Problems? 59:04 Russell Impagliazzo, UC San Diego
The Contextual Bandits Problem 54:29
In Pursuit of Structure: Why a Little Randomness (Almost) Always Helps 51:05
Does Computational Complexity Restrict Artificial Intelligence (AI) and Machine Learning? 52:08

Invisibility: The Power of an Idea | The New School

# click the upper-left icon to select videos from the playlist

source: The New School 2017年5月4日
There is nothing more magical than the lure and power of invisibility, and no stronger weapon. It challenges our scientific imagination to new ways of revealing and concealing—penetrating the unseen mysteries of black holes and gravitational waves, cloaking what we wish to hide from our adversaries. It infuses our literature and drives the mythical and religious underpinnings of culture. And by stripping populations of their place in society—the invisible “other” in the form of African Americans, women in Saudi Arabia, the homeless, veterans—it spurs us to action, to create change for the better. Join us as we investigate the concept of invisibility and interrogate what’s seen, what’s unseen, what’s unseeable, and what we do in response.
Visit the Center for Public Scholarship (http://centerforpublicscholarship.org) for more information.

Invisibility: The Power of an Idea - Cultural Context 1:56:29
Invisibility: The Power of an Idea - Keynote with Brian Greene 1:26:44
Invisibility: The Power of an Idea - Social World 2:02:33
Invisibility: The Power of an Idea - The Seen, the Unseen and the The Unseeable 1:26:26
Invisibility: The Power of an Idea - Research and Discovery 1:59:08

Zero Waste Food Conference | The New School

# click the upper-left icon to select videos from the playlist

source: The New School 2017年5月8日
Presented by the Institute of Culinary Education (https://ice.edu/) and the Food Studies Program (http://newschool.edu/public-engagement/ba-bs-food-studies/) in The Schools of Public Engagement (http://newschool.edu/public-engagement/) in collaboration with the Tishman Environment and Design Center (https://newschool.edu/tishman-environment-design-center/).
Creating more sustainable food networks is one of the crucial challenges of the 21st century.
The New School | http://newschool.edu
Zero Waste Food will bridge the gap between research and practice, and draw upon the perspectives of academia, activism, food business, chefs and food producers, in order to synthesize our shared goals and strategies. Throughout the conference, luminaries in the food industry will share their ideas for change and their visions of the future. Whether you’re a student, employed in the food industry or simply passionate about food, the conference will equip you with valuable lessons and skills to apply to your daily lives and business practices.
We want to do more than talk about food waste. We want to give you the tools to help solve the problem.
In an ever-evolving industry, the Zero Waste Food conference will present a fresh perspective on food waste and sustainability, and create a community of like-minded scholars, culinary professionals, and food lovers. What’s more, we’ll give you the tools to incorporate our shared vision into your daily practices.

Keynote with Massimo Bottura 1:00:31
Reimagining Sustainable Restaurant Kitchens 1:22:27
Reimagining Sustainable Connections Within Food Chains 1:02:48
Repurposing Food Waste 1:23:42
Repurposing Spaces and Materials 1:32:23

East Tennessee State University (videos of April 2017)

source: East Tennessee State University

Breakfast with the Expert-April 26, 2017-Allison Rogers (Part 2)

11:25 Final 2part Allison Rogers BWE Allison Rogers, Vice President, Strategic Planning, MSHA

8:22 Allison Rogers 4-26-17 Allison Rogers, Vice President, Strategic Planning, MSHA

3:03 Breakfast with the Expert, Allison Rogers, 4-26-17 Allison Rogers, Vice President, Strategic Planning, MSHA

36:41 Lecture 23, Subroutines

7:32 WarfarinDosing Warfarin, dose calculation, single nucleotide polymorphysims, SNP, genetis, 23andMe, Ancestry, cytochromes, Vitamin K, Vitamin k reductase, David Johnson

8:18 Warfarin and Blood Coagulation Warfarin, Vitamin K, Blood Clotting, Pharmacogenomics, David Johnson, Prothrombin Time, INR, Biochemistry

47:16 Lecture 22, ALV Grids

39:16 Lecture 21, ABAP Objects Polymorphism

43:28 Women on Wednesdays - Lindsey Devine - ETSU Volleyball Lindsey Devine - ETSU Volleyball Program - Head Coach
ETSU women’s volleyball head coach Lindsey Devine will speak on “Power of Passion – Pillars of Success” in the “Women on Wednesdays” lecture s...

58:03 Women on Wednesdays - Dr. Lorianne Mitchell Horse before the Carriage?: The role of higher education in advancing diversity and inclusion in society.
This is the seventh of nine free public talks to be given in the “Women on Wednesdays” Lec...

37:15 Lecture 20, ABAP Class Builder

7:08 Discovery Studio Visualizer How to use Discovery Studio Visualizer, molecular Modeling, Dr. David Johnson, Biomedical Sciences, Quillen College of Medicine

15:10 Basic Alpha Helix Beta Sheet Protein Structure Protein Secondary Structures, Amino Acids, Peptides, Dr. David Johnson, Biomedical Sciences, Quillen College of Medicine

27:09 Protein Purification and Characterization 2014 How to purify proteins and enzymes; Dr. David Johnson, Biomedical Sciences, Quillen College of Medicine

11:04 Methemoglobinemia in the Blue People of Troublesome Creek Kentucky Hemoglobinopathy, Dr. David Johnson, Biomedical Sciences, Quillen College of Medicine

1:02:59 Lecture 19, ABAP Objects Inheritance

26:08 ANTH 4957 - Human Nutrition

34:35 ANTH 4957 - Health & Disease

38:15 ANTH 4957 - Variation in Growth

17:04 Amino Acid Big Picture 2017
Review of Amino Acid Metabolism in 17 minutes; Step1 Review, Medical, Diseases, vitamins, UREA Cycle, Biochemistry, PKU, Maple Syrup

The Normans by Sally Vaughn (U of Houston)

# playlist of the 28 videos (click the upper-left icon of the video)

source: UHouston 2008年12月18日
HIST 4331
Title: The Normans
Professor: Sally Vaughn
Description: Normans from their Viking origins through their conquests in northern Europe, the Mediterranean, North Africa, and the Middle East: state-building in these regions, cultural achievements, the role of women, and impact on world history.

World Revolutions by Thomas O'Brien (U of Houston)

# playlist of the 26 videos (click the upper-left icon of the video)

source: UHouston 2009年4月22日
HIST 3394/3383
Title: World Revolutions
Professor: Thomas O'Brien
Description: Causes and effects of modern revolutions from the English Civil War of the 17th century to the Iranian Revolution at the end of the 20th century.

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