Freshman Organic Chemistry (Fall 2008) by Michael McBride at Yale University

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source: YaleCourses    Last updated on 2014年7月2日

Freshman Organic Chemistry (CHEM 125)

This is the first semester in a two-semester introductory course focused on current theories of structure and mechanism in organic chemistry, their historical development, and their basis in experimental observation. The course is open to freshmen with excellent preparation in chemistry and physics, and it aims to develop both taste for original science and intellectual skills necessary for creative research. Complete course materials are available at the Open Yale Courses website: http://open.yale.edu/courses

1. How Do You Know? 46:41

2. Force Laws, Lewis Structures and Resonance 50:13

3. Double Minima, Earnshaw's Theorem and Plum-Puddings 45:03

4. Coping with Smallness and Scanning Probe Microscopy 50:02

5. X-Ray Diffraction 47:10

6. Seeing Bonds by Electron Difference Density 51:10

7. Quantum Mechanical Kinetic Energy 49:18

8. One-Dimensional Wave Functions 49:51

9. Chladni Figures and One-Electron Atoms 49:36

10. Reality and the Orbital Approximation 48:34

11. Orbital Correction and Plum-Pudding Molecules 49:27

12. Overlap and Atom-Pair Bonds 50:35

13. Overlap and Energy-Match 49:44

14. Checking Hybridization Theory with XH_3 47:36

15. Chemical Reactivity: SOMO, HOMO, and LUMO 47:12

16. Recognizing Functional Groups 50:09

17. Reaction Analogies and Carbonyl Reactivity 41:44

18. Amide, Carboxylic Acid and Alkyl Lithium 51:21

19. Oxygen and the Chemical Revolution (Beginning to 1789) 47:10

20. Rise of the Atomic Theory (1790-1805) 50:01

21. Berzelius to Liebig and Wöhler (1805-1832) 49:22

22. Radical and Type Theories (1832-1850) 49:15

23. Valence Theory and Constitutional Structure (1858) 48:47

24. Determining Chemical Structure by Isomer Counting (1869) 50:15

25. Models in 3D Space (1869-1877); Optical Isomers 49:02

26. Van't Hoff's Tetrahedral Carbon and Chirality 48:27

27. Communicating Molecular Structure in Diagrams and Words 51:36

28. Stereochemical Nomenclature; Racemization and Resolution 47:30

29. Preparing Single Enantiomers and the Mechanism of Optical Rotation 50:19

30. Esomeprazole as an Example of Drug Testing and Usage 50:43

31. Preparing Single Enantiomers and Conformational Energy 48:53

32. Stereotopicity and Baeyer Strain Theory 46:18

33. Conformational Energy and Molecular Mechanics 47:53

34. Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes 49:18

35. Understanding Molecular Structure and Energy through Standard Bonds 48:42

36. Bond Energies, the Boltzmann Factor and Entropy 47:51

37. Potential Energy Surfaces, Transition State Theory and Reaction Mechanism 47:44